Neutrophil activity와 recruitment 연구를 위한 ELISA Kit

호중구(neutrophil)는 급성 염증의 특징입니다. 호중구는 식세포작용, 탈과립화 및 호중구 세포외 트랩(NET)의 방출을 통해 침입하는 미생물을 제거하기 위해 염증 부위로 모집됩니다.

새로운 연구에 따르면 호중구(또는 NET)는 죽상경화증, 당뇨병, 비알코올성 지방간 질환(NAFLD) 및 자가면역 질환과 같은 다양한 만성 염증성 질환과 관련이 있습니다. 게다가 여러 보고서에 따르면 종양 관련 호중구는 많은 유형의 암에서 생존율이 낮습니다. 호중구를 표적으로 삼는 것은 이러한 질병에 대한 새로운 치료적 접근 방식이 되고 있습니다.

Arigo는 호중구 활동, 모집 및 자가항체의 검사를 용이하게 하는 일련의 ELISA 키트를 제공합니다.

Neutrophil Activity 측정

ELISA Kit	Human	Mouse
MPO	ARG82988	ARG81785
MPO Activity Assay Kit	ARG82770
Neutrophil Elastase	ARG82775	ARG81927
NGAL	ARG80941	ARG81764
Defensin	AD-1 (ARG82004) BD-1 (ARG80905) BD-2 (ARG80903) BD-3 (ARG82252) BD-4 (ARG80902)

Neutrophil chemoattractants 측정

ELISA Kit	Human	Mouse	Rat
IL-8	ARG83357
CXCL1		ARG80208	ARG80236
CXCL2		ARG80221	ARG83230
CXCL5		ARG81777	ARG81751
G-CSF	ARG80143	ARG81277

Visualization of neutrophils in tissues

• Neutrophil markers

MPO antibody [SP72] (ARG53344)

Neutrophil Elastase antibody (ARG40838)

• Neutrophil in inflammation

Neutrophils are early inflammatory cells. An increase of neutrophils is a critical indicator of acute inflammation. arigo’s inflammatory cell antibody panels comprise the inflammatory cell markers including a neutrophil marker.

Human Inflammatory Cell Antibody Panel
(ARG30325)

Mouse Inflammatory Cell Antibody Panel
(ARG30326)

• Antibody duos for neutrophil

MDSCs share the same markers with neutrophils. arigo’s MDSC antibody duos can be applied for labeling neutrophils in tissues.

Human MDSC Marker Antibody Duo
(ARG30336)

Mouse MDSC Marker Antibody Duo
ARG30335)

Quantification of neutrophil degranulation

Neutrophils contain several subsets of granules in which store antimicrobial cytotoxic. Once activated, neutrophils release these granules to destroy the pathogens (a process called degranulation). Excessive neutrophil degranulation results to tissue damage and is a feature of many inflammatory disorders including severe asthma, COPD, rheumatoid arthritis. arigo offers quality ELISA kits for the quantification of neutrophil degranulation to facilitate the research and therapeutic development of neutrophil-associated inflammatory diseases.

Target	Product	Cat. No.
Azurocidin	Human Azurocidin ELISA Kit	ARG81827
Defensin	Human AD-1 ELISA Kit	ARG82004
	Human BD-1 ELISA kit	ARG80905
	Human BD-2 ELISA kit	ARG80903
	Human BD-3 ELISA Kit	ARG82252
	Human BD-4 ELISA kit	ARG80902
Elastase	Human Neutrophil Elastase ELISA Kit	ARG82775
Elastase	Mouse Neutrophil Elastase ELISA Kit	ARG81927
MPO	MPO Activity Assay Kit (Colorimetric)	ARG82770
	MPO Activity Assay Kit (Fluorometric)	ARG82771
	Human MPO ELISA Kit	ARG82988
	Mouse MPO ELISA Kit	ARG81785